Cerebrolysin
A neuropeptide preparation that mimics endogenous neurotrophic factors to promote brain protection, repair, and neurogenesis.
Cerebrolysin is a parenterally administered mixture of low-molecular-weight neuropeptides and free amino acids derived from purified brain proteins. It is approved in over 40 countries for the treatment of stroke, traumatic brain injury, and dementia. Multiple randomized controlled trials and meta-analyses have demonstrated its efficacy in improving neurological outcomes after ischemic stroke.
⚙️ Mechanism of Action
Cerebrolysin mimics the action of endogenous neurotrophic factors including BDNF and CNTF, promoting neuronal survival, synaptic plasticity, and neurogenesis. It reduces beta-amyloid deposition and tau phosphorylation by regulating GSK-3beta and CDK5 activity. The peptide also stimulates neural progenitor cell proliferation in the subventricular zone and promotes migration of neuroblasts to damaged brain areas.
✅ Benefits
- •Promotes neurogenesis and neural repair after stroke
- •Improves cognitive function in dementia patients
- •Enhances synaptic density and neuronal cytoarchitecture
- •Reduces neuroinflammation
- •Supports recovery from traumatic brain injury
- •Well-established safety profile across large clinical trials
⚠️ Risks & Considerations
- •Dizziness and headache
- •Injection site reactions
- •Nausea
- •Agitation or insomnia (rare)
📚 References
Latest Videos
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