AOD-9604
A modified fragment of human growth hormone (hGH 176-191) that stimulates lipolysis and fat oxidation without affecting blood sugar or growth.
AOD-9604 is a synthetic peptide derived from the C-terminal fragment of human growth hormone, specifically designed to retain fat-burning properties while eliminating growth-promoting effects. It has been shown to reduce body weight, increase fat oxidation, and stimulate lipolysis in both animal models and human trials. Notably, it does not interact with the GH receptor or affect IGF-1 levels.
⚙️ Mechanism of Action
AOD-9604 mimics the lipolytic action of natural growth hormone by stimulating fat breakdown in adipose tissue through a mechanism independent of the GH receptor. It increases fat oxidation and reduces lipogenesis without the metabolic side effects associated with full-length GH, such as insulin resistance or elevated IGF-1. The peptide selectively targets fat metabolism pathways while leaving glucose homeostasis unaffected.
✅ Benefits
- •Stimulates fat breakdown and oxidation
- •Does not affect IGF-1 or blood sugar levels
- •Excellent safety and tolerability profile in clinical trials
- •May support joint and cartilage repair
- •No impact on appetite or lean mass
⚠️ Risks & Considerations
- •Mild injection site reactions
- •Headache
- •Chest tightness (rare)
- •Indigestion
📚 References
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